Quinone and hydroquinone lipids
Medchemexpress LLC DL-alpha-Tocopherol 5g | 1309573-60-1 | 5 G
DL-alpha-tocopherol methoxypolyethylene glycol succinate is a vitamin E-derived amphiphilic surfactant and solubilizing agent supplied as an aqueous solution for research use; it is used to aid solubilization, improve reaction performance, and support stability testing of modified drugs.
- Acts as an amphiphilic surfactant and solubilizer.
- Improves aqueous solubility of lipophilic compounds.
- Enhances aqueous cross-coupling reaction performance (Suzuki-Miyaura reported).
- Used for stability testing of modified drugs in biological fluids.
- Typically provided as an aqueous solution at about 20 mg/mL.
Medchemexpress LLC Vosoritide (acetate) | 99.89% | 4162.78 | 25 MG
Vosoritide acetate is a natriuretic peptide receptor 2 (NPR2) agonist that promotes bone growth by acting on the proliferation and differentiation of chondrocytes. It is for research use only.
- Decreases NPR2 phosphorylation in chondrocytes.
- Improves chondrocyte differentiation and increases growth plate area.
- Reduces ERK1/2 activation in growth-plate chondrocytes.
- Improves skeletal parameters in Fgfr3 gain-of-function mutation mouse model.
Medchemexpress LLC Mait-203 acetate | 98.0% | 2517.23 | 5 MG
MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic that inhibits APC-Asef interaction and represses colorectal cancer cell migration and invasion.
- Potently inhibits APC-Asef interaction.
- Binds APC-ARM with Ki of 0.015 μM and Kd of 0.036 μM.
- Represses migration and invasion of colorectal cancer cells.
- Reduces Asef-APC interaction in HEK293T cells.
- Attenuates SW480 and HCT116 cell migration.
- Decreases active CDC42 in SW480 cells.
- Keep container tightly sealed in cool, well-ventilated area.
- Keep away from direct sunlight and sources of ignition.
- Store powder at -80°C for 2 years or -20°C for 1 year.
- Store in solvent at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture).
- Ship at room temperature if less than 2 weeks.
![eMolecules 1219794-57-6 | Tolbutamide-d9 | Toronto Research Chemicals | MFCD06658779 | 279.400 | C12H18N2O3S | 95.000 | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(=O)NS(=O)(=O)c1ccc(C)cc1 | 2.5mg | 882925946](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 1219794-57-6 | Tolbutamide-d9 | Toronto Research Chemicals | MFCD06658779 | 279.400 | C12H18N2O3S | 95.000 | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(=O)NS(=O)(=O)c1ccc(C)cc1 | 2.5mg | 882925946
Tolbutamide-d9 | Toronto Research Chemicals | 1219794-57-6 | MFCD06658779 | 279.400 | C12H18N2O3S | 95.000 | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(=O)NS(=O)(=O)c1ccc(C)cc1 | 2.5mg | 882925946
Medchemexpress LLC A11 (acetate) | 2412926-30-6 | 98.5% | 2767.16 | 5 MG
A11 acetate is an ANXA1-EphA2 interaction blocker peptide that inhibits nasopharyngeal carcinoma (NPC) cell proliferation, migration, invasion, and angiogenesis.
- Decreases ANXA1 bound to EphA2
- Increases Cbl bound to EphA2
- Decreases EphA2 levels and increases EphA2 ubiquitination
- Increases EphA2 internalization and colocalization with Cbl in NPC cells
- Inhibits NPC cell proliferation
- Inhibits migration, invasion, and angiogenesis
Medchemexpress LLC RI-AG03 acetate | 98.2% | 2477.93 | 5 MG
RI-AG03 acetate is the acetate of RI-AG03, an orally active and BBB-penetrable Tau aggregation peptide inhibitor. It inhibits Tau aggregation and improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models. This product can be used in the study of tauopathies such as Alzheimer's disease.
- Orally active
- BBB-penetrable Tau aggregation peptide inhibitor
- Inhibits Tau aggregation
- Improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models
- Can be used in the study of tauopathies such as Alzheimer's disease
Cayman Chemical PentnoIc AcId-d9 100mg
An internal standard for the quantification of pentanoic acid by GC- or LC-MS
Medchemexpress LLC ATIC-IN-1 acetate | 3067165-96-9 | C23H37N7O7 | 25 MG
ATIC-IN-1 acetate, also known as compound 14, is an inhibitor that targets the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). This dimerization is crucial for the AICAR transformylase activity of ATIC, which plays a role in de novo purine biosynthesis. It demonstrates anti-tumor activity by reducing cell numbers and cell division rates.
- Inhibits ATIC dimerization with a Ki value of 685 nM
- Exhibits anti-tumor activity
- Reduces cell numbers and cell division rates
- Can be used in research to study ATIC dimerization and its role in purine biosynthesis and tumor proliferation
- Inhibits the proliferation of MCF-7 cells at concentrations of 100-500 μM over 48 hours
- At 250 μM for 24-72 hours, it reduces cell division rather than increasing cell death
Medchemexpress LLC PRT062607 (acetate) | 1370261-98-5 | C21H27N9O3 | 5 MG
PRT062607 acetate is a laboratory chemical used for the manufacture of substances. It is classified as not a hazardous substance or mixture and is intended for research use only by experienced personnel.
- Stable under recommended storage conditions
- Suitable for high-speed applications
- Available as a solid appearance
- Shipped at room temperature if less than 2 weeks
Medchemexpress LLC Cetrorelix Acetate | 145672-81-7 | 99.9% | 1491.09 | 5 MG
Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. It inhibits the growth of ES-2 cell lines at 1000 ng/ml, demonstrating comparable antiproliferative effects to GnRH-I agonists.
- Potent gonadotropin-releasing hormone (GnRH) receptor antagonist
- Exhibits IC50 of 1.21 nM against GnRH
- Inhibits growth of ES-2 cell line at 1000 ng/ml
- Soluble in DMSO and H2O
Medchemexpress LLC Rel-PROTAC PARP1 degrader | 99.0% | 1145.09 | 10 MG
rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand.
- Induces significant PARP1 cleavage.
- Induces programmed cell death.
- Inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM at 10 μM within 24 hours.
- For research use only.
Medchemexpress LLC (±)-α-Tocopherol acetate (Standard) | 7695-91-2 | 98.9% | 50 MG
This (±)-α-Tocopherol acetate (Standard) is presented as a colorless to light yellow liquid, characterized by its molecular formula C31H52O3 and a molecular weight of 472.74. It is supplied in a brown glass bottle, with storage recommendations at -20°C in sealed conditions, protected from light and moisture. The product exhibits a high purity, verified through an assay of 98.53% and an HPLC purity of 98.86%.
- Colorless to light yellow liquid
- Precise molecular formula of C31H52O3
- Molecular weight of 472.74
- Packaged in a brown glass bottle for optimal preservation
- Recommended storage at -20°C in sealed conditions, away from light and moisture
- High purity of 98.86% (HPLC)
- Traceable to ISO 17025 requirements for calibration
Medchemexpress LLC MK2-IN-5 acetate (Hsp25 kinase inhibitor acetate) | 99.6% | 1396.68 (free base) | 5 MG
MK2-IN-5 acetate is identified as a Mk2 pseudosubstrate with a Ki of 8 μM. This compound specifically targets the protein interaction domain within the MAPK pathway and functions by inhibiting the phosphorylation of both HSP25 and HSP27.
- Inhibits TGF-b1 induced connective tissue growth factor (CTGF) and collagen type I in primary human keloid fibroblasts (at 5-10 μM, 2 hours).
- Decreased HSP25 phosphorylation in a ventilator-associated lung injury model with a single intraperitoneal injection (2 mg/kg).
Abcam Vitamin E (DL-alpha-Tocopherol), Fat-soluble antio x idant, 25G
MW 430.7 Da, Purity >98%. Fat-soluble antioxidant. Peroxyl radical scavenger that protects polyunsaturated fatty acids in membranes and lipoproteins. Anticarcinogen.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC BMP-4 acetate | 99.3% | 1308.52 (free base) | 5 MG
BMP-4 acetate is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. It regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6, effectively suppressing inflammation and alleviating various arthritis symptoms in murine chondrocytes and macrophages.
- Penetrating heparin-binding peptide
- Anti-inflammatory and anti-chondrogenic functions
- Regulates iNOS-IFN-IL6 signaling pathway
- Inhibits inflammatory proteins like iNOS, COX2, IFN, and IL6
- Alleviates arthritis symptoms in murine chondrocytes and macrophages